Sequence tag–based analysis of microbial population dynamics
نویسندگان
چکیده
منابع مشابه
STAMP: Sequence tag-based analysis of microbial population dynamics
We describe a new method (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the frequency changes of genetically “barcoded” organisms to quantify population bottlenecks and infer the founding population size. Analyses of intra-intestinal Vibrio cholerae revealed infection-stage and region-specific host barriers to infection, and unexpectedly showed V. ...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2015
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.3253